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SELECTED PUBLICATIONS
 

Gates LA#, Reis BS, Lund PJ, Paul MR, Leboeuf M, Djomo AM, Nadeem Z, Lopes M, Vitorino FN, Unlu G, Carroll TS, Birsoy K, Garcia BA, Mucida D, Allis CD (2024). Histone butyrylation in the mouse intestine is mediated by the microbiota and associated with regulation of gene expression.  Nature Metabolism, https://doi.org/10.1038/s42255-024-00992-2. #Corresponding author.

 

Lund PJ, Gates LA, Leboeuf M, Smith SA, Chau L, Friedman ES, Lopes M, Saiman Y, Kim MS, Petucci, Allis CD, Wu GD, Garcia BA (2022). Stable Isotope Tracing in vivo Reveals A Metabolic Bridge Linking the Microbiota to Host Histone Acetylation. Cell Reports, 41, 111809.

 

Soto-Feliciano YM, Sánchez-Rivera FJ, Perner F, Barrows DW, Kastenhuber ER, Ho YJ, Carroll T, Xiong Y, Anand D, Soshnev S, Gates L, Beytagh MC, Cheon D, Gu S, Liu XS, Krivtsov AV, Meneses M, de Stanchina E, Stone RM, Armstrong SA, Lowe SW, Allis CD (2022). A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition. Cancer Discovery.

 

Burton AJ, Haugbro M, Gates LA, Bagert JD, Allis CD, Muir TW (2020). In situ chromatin interactomics using a chemical bait and trap approach. Nature Chemistry, 12:520-527.

 

Williams RT, Guarecuco R, Gates LA, Barrows D, Passarelli MC, Carey B, Baudrier L, Jeewajee S, La K, Prizer B, Malik S, Garcia-Bermudez J, Zhu XG, Cantor J, Molina H, Carroll T, Roeder RG, Abdel-Wahab O, Allis CD, Birsoy K (2020). ZBTB1 Regulates Asparagine Synthesis and Leukemia Cell Response to L-Asparaginase. Cell Metabolism, 31:852-61.

 

Wan L, Chong S, Xuan F, Liang A, Cui X, Gates L, Carroll T, Li Y, Feng L, Chen G, Wang S, Ortiz M, Daley S, Wang X, Xuan H, Kentsis A, Muir TW, Roeder RG, Li H, Li W, Tjian R, Wen H#, Allis CD# (2020). Impaired cell fate through gain-of-function mutations in a chromatin reader. Nature, 577:121-126. #Co-corresponding authors.

 

Gates LA*, Gu G*, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang, SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SA, O’Malley BW, Foulds CE (2018). Proteomic profiling identifies key coactivators utilized by mutant ERα proteins as potential new therapeutic targets. Oncogene, 37:4581–4598. *co-first authors.

 

Gates LA, Foulds CE, O’Malley BW (2017). Histone marks in the ‘drivers’ seat: functional roles in steering the transcription cycle. Trends in Biochemical Sciences, 42: 977-989.

 

Gates LA, Shi J, Rohira A, Feng Q, Zhu B, Bedford MT, Sagum CA, Jung SY, Qin J, Tsai MJ, Tsai SY, Li W, Foulds, CE, O’Malley, BW (2017). Acetylation on histone H3 lysine 9 mediates a switch from transcription initiation to elongation. Journal of Biological Chemistry, 292: 14456-14472.

 

Foulds CE, Feng Q, Chen D, Bailey S, Hunsaker TL, Malovannaya A, Hamilton RA, Gates LA, Zhang Z, Li C, Chan D, Bajaj A, Callaway C, Edwards DP, Lonard DM, Tsai SY, Tsai MJ, Qin J, O’Malley BW (2013). Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics. Molecular Cell, 51: 185-99.

Complete list of publications: https://www.ncbi.nlm.nih.gov/myncbi/leah.gates.1/bibliography/public/

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